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Furthermore, disruption in the CR process leads to the production of higher CTCs, particularly during sleep time, which can further promote the tumor progression as these CTCs display elevated expression of circadian hormone receptors, and hormones such as melatonin modulate their release (174, 175)

Imaging techniques (i.e., ERCP) have also shown biliary tract calculi in many patients with established PSC, suggesting the removal of calculi as an exclusionary criterion (Kaw et al, 1995)

The data were presented as the fold change in the tested group compared with the control group

This impairment leads to the accumulation of dysfunctional mitochondria, exacerbating oxidative stress and inflammation [227]

Quanti mg vi siano contenuti dipende dalla preparazione